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NK cells require IL-28R for optimal in vivo activity

Natural killer (NK) cells are naturally circulating innate lymphoid cells that protect against tumor initiation and metastasis and contribute to immunopathology during inflammation. The signals that prime NK cells are not completely understood, and, although the importance of IFN type I is well reco...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Souza-Fonseca-Guimaraes, Fernando, Young, Arabella, Mittal, Deepak, Martinet, Ludovic, Bruedigam, Claudia, Takeda, Kazuyoshi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Hill, Geoffrey R., Smyth, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426428/
https://ncbi.nlm.nih.gov/pubmed/25901316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424241112
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