NK cells require IL-28R for optimal in vivo activity

Natural killer (NK) cells are naturally circulating innate lymphoid cells that protect against tumor initiation and metastasis and contribute to immunopathology during inflammation. The signals that prime NK cells are not completely understood, and, although the importance of IFN type I is well reco...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Souza-Fonseca-Guimaraes, Fernando, Young, Arabella, Mittal, Deepak, Martinet, Ludovic, Bruedigam, Claudia, Takeda, Kazuyoshi, Andoniou, Christopher E., Degli-Esposti, Mariapia A., Hill, Geoffrey R., Smyth, Mark J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426428/
https://ncbi.nlm.nih.gov/pubmed/25901316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424241112
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