Cathepsin C limits acute viral infection independently of NK cell and CD8(+) T‐cell cytolytic function

Destruction of target cells by cytotoxic T lymphocytes (CTLs) or natural killer (NK) cells requires the coordinated action of the pore forming protein perforin (Pfp) and the granzyme (Gzm) family of serine proteases. The activation of a number of serine proteases, including GzmA and B, is predominat...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Andoniou, Christopher E, Fleming, Peter, Sutton, Vivien R, Trapani, Joseph A, Degli‐Esposti, Mariapia A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165893/
https://ncbi.nlm.nih.gov/pubmed/20975734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.115
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