Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations.

We tested the in vitro susceptibility of Candida albicans to three defensins from human neutrophilic granulocytes (HNP-1, 2, and 3), a homologous defensin from rabbit leukocytes (NP-1), and four unrelated cationic peptides. Although the primary amino acid sequences of HNP-1, 2, and 3 are identical e...

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Опубликовано в::	J Clin Invest
Главные авторы:	Lehrer, R I, Ganz, T, Szklarek, D, Selsted, M E
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 1988
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290255/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113527
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