Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations.

We tested the in vitro susceptibility of Candida albicans to three defensins from human neutrophilic granulocytes (HNP-1, 2, and 3), a homologous defensin from rabbit leukocytes (NP-1), and four unrelated cationic peptides. Although the primary amino acid sequences of HNP-1, 2, and 3 are identical e...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Lehrer, R I, Ganz, T, Szklarek, D, Selsted, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442632/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3290255/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113527
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