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Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity.

Defensins are small, cysteine-rich antimicrobial peptides that are abundant in human, rabbit, and guinea pig neutrophils (PMN). Three defensins (human neutrophil peptide defensin [HNP]-1, HNP-2, and HNP-3) constitute between 30 and 50% of the total protein in azurophil granules of human PMN. We exam...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Lehrer, R I, Barton, A, Daher, K A, Harwig, S S, Ganz, T, Selsted, M E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2668334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114198
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