Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis

AIM: Aberrant methylation of the promoter, P2, and the first exon, E1, regions of the tumor suppressor gene RASSF1A, have been associated with hepatocellular carcinoma (HCC), albeit with poor specificity. This study analyzed the methylation profiles of P1, P2 and E1 regions of the gene to identify t...

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Bibliografiska uppgifter
I publikationen:Hepatol Res
Huvudupphovsmän: Jain, Surbhi, Xie, Lijia, Boldbaatar, Batbold, Lin, Selena Y., Hamilton, James P., Meltzer, Stephen J., Chen, Shun-Hua, Hu, Chi-Tan, Block, Timothy M., Song, Wei, Su, Ying-Hsiu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426255/
https://ncbi.nlm.nih.gov/pubmed/25382672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hepr.12449
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