Polymerization of sickle cell hemoglobin at arterial oxygen saturation impairs erythrocyte deformability.
We have examined the filterability of sickle erythrocytes, using an initial-flow-rate method, to determine whether sufficient hemoglobin S polymer forms at arterial oxygen saturation to adversely affect erythrocyte deformability. The amount of intracellular polymer was calculated as a function of ox...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1988
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3384944/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113504 |
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