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Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells

BACKGROUND: Cancer cells exhibit increased glycolysis for ATP production (the Warburg effect) and macromolecular biosynthesis; it is also linked with therapeutic resistance that is generally associated with compromised respiratory metabolism. Molecular mechanisms underlying radio-resistance linked t...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Bhatt, Anant Narayan, Chauhan, Ankit, Khanna, Suchit, Rai, Yogesh, Singh, Saurabh, Soni, Ravi, Kalra, Namita, Dwarakanath, Bilikere S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425929/
https://ncbi.nlm.nih.gov/pubmed/25925410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1368-9
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