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TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways

Connective tissue growth factor (CTGF), which is also called CCN2, is a secreted matricellular protein. CTGF regulates various important cellular functions by interacting with multiple molecules in the microenvironment. In the ovary, CTGF is mainly expressed in granulosa cells and involved in the re...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Cheng, Jung-Chien, Chang, Hsun-Ming, Fang, Lanlan, Sun, Ying-Pu, Leung, Peter C. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425519/
https://ncbi.nlm.nih.gov/pubmed/25955392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126532
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