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hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS

Sprouty2 (SPRY2) is an important intracellular regulator for epidermal growth factor receptor (EGFR)-mediated ERK1/2 signaling. In human granulosa cells, although SPRY2 is expressed, its regulation and function remains complete unknown and must be defined. Our previous study has shown that human cho...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cheng, Jung-Chien, Fang, Lanlan, Chang, Hsun-Ming, Sun, Ying-Pu, Leung, Peter C. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4990972/
https://ncbi.nlm.nih.gov/pubmed/27539669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31675
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