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TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways

Connective tissue growth factor (CTGF), which is also called CCN2, is a secreted matricellular protein. CTGF regulates various important cellular functions by interacting with multiple molecules in the microenvironment. In the ovary, CTGF is mainly expressed in granulosa cells and involved in the re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cheng, Jung-Chien, Chang, Hsun-Ming, Fang, Lanlan, Sun, Ying-Pu, Leung, Peter C. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425519/
https://ncbi.nlm.nih.gov/pubmed/25955392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126532
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