Fine Mapping of a GWAS-Derived Obesity Candidate Region on Chromosome 16p11.2

INTRODUCTION: Large-scale genome-wide association studies (GWASs) have identified 97 chromosomal loci associated with increased body mass index in population-based studies on adults. One of these SNPs, rs7359397, tags a large region (approx. 1MB) with high linkage disequilibrium (r²>0.7), which c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Volckmar, Anna-Lena, Song, Jie-Yun, Jarick, Ivonne, Pütter, Carolin, Göbel, Maria, Horn, Lucie, Struve, Christoph, Haas, Katharina, Knoll, Nadja, Grallert, Harald, Illig, Thomas, Reinehr, Thomas, Wang, Hai-Jun, Hebebrand, Johannes, Hinney, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425372/
https://ncbi.nlm.nih.gov/pubmed/25955518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125660
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