Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants

BACKGROUND: The SH2B1 gene (Src-homology 2B adaptor protein 1 gene) is a solid candidate gene for obesity. Large scale GWAS studies depicted markers in the vicinity of the gene; animal models suggest a potential relevance for human body weight regulation. METHODS: We performed a mutation screen for...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Volckmar, Anna-Lena, Bolze, Florian, Jarick, Ivonne, Knoll, Nadja, Scherag, André, Reinehr, Thomas, Illig, Thomas, Grallert, Harald, Wichmann, Heinz-Erich, Wiegand, Susanna, Biebermann, Heike, Krude, Heiko, Fischer-Posovszky, Pamela, Rief, Winfried, Wabitsch, Martin, Klingenspor, Martin, Hebebrand, Johannes, Hinney, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544595/
https://ncbi.nlm.nih.gov/pubmed/23270367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-65
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados