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Chipping Away the ‘Missing Heritability’: GIANT Steps Forward in the Molecular Elucidation of Obesity – but Still Lots to Go

Although heritability of human body weight is assumed to be high, only a small fraction of the variance can as yet be attributed to molecular genetic factors. Single monogenic forms of obesity have been identified. Functionally relevant coding mutations in the melanocortin-4 receptor gene occur in 1...

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Detalhes bibliográficos
Publicado no:Obes Facts
Main Authors: Hebebrand, Johannes, Volckmar, Anna-Lena, Knoll, Nadja, Hinney, Anke
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452141/
https://ncbi.nlm.nih.gov/pubmed/20975295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000321537
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