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Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells.

The experimental metastasis of B16-F10 murine melanoma cells is blocked by the anti-cell adhesive pentapeptide Gly-Arg-Gly-Asp-Ser (GRGDS) derived from the central cell-binding domain of fibronectin. In this report, we show that peptide treatment substantially extends the survival time for mice inje...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Humphries, M J, Yamada, K M, Olden, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442526/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3343338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113384
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