Total Synthesis of ( + )-Swainsonine, (–)- Swainsonine, ( + )-8--
A tactical combination of either ( S )- or ( R )-proline catalyzed aldol reaction followed by intramolecular reductive amination enabled the synthesis of a chiral pyrrolidine derivative with 3 contiguous stereocenters in only 2 synthetic steps, starting from achiral precursors. This product, obtaina...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publishing
2022-04-01
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| coleção: | Natural Product Communications |
| Acesso em linha: | https://doi.org/10.1177/1934578X221091672 |
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