Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells.

The experimental metastasis of B16-F10 murine melanoma cells is blocked by the anti-cell adhesive pentapeptide Gly-Arg-Gly-Asp-Ser (GRGDS) derived from the central cell-binding domain of fibronectin. In this report, we show that peptide treatment substantially extends the survival time for mice inje...

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Pubblicato in:	J Clin Invest
Autori principali:	Humphries, M J, Yamada, K M, Olden, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442526/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3343338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113384
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