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Building a Pan-Genome Reference for a Population

A reference genome is a high quality individual genome that is used as a coordinate system for the genomes of a population, or genomes of closely related subspecies. Given a set of genomes partitioned by homology into alignment blocks we formalize the problem of ordering and orienting the blocks suc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Comput Biol
Hauptverfasser: Nguyen, Ngan, Hickey, Glenn, Zerbino, Daniel R., Raney, Brian, Earl, Dent, Armstrong, Joel, Kent, W. James, Haussler, David, Paten, Benedict
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424974/
https://ncbi.nlm.nih.gov/pubmed/25565268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2014.0146
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