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Representing and decomposing genomic structural variants as balanced integer flows on sequence graphs

BACKGROUND: The study of genomic variation has provided key insights into the functional role of mutations. Predominantly, studies have focused on single nucleotide variants (SNV), which are relatively easy to detect and can be described with rich mathematical models. However, it has been observed t...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Zerbino, Daniel R., Ballinger, Tracy, Paten, Benedict, Hickey, Glenn, Haussler, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043639/
https://ncbi.nlm.nih.gov/pubmed/27687569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1258-4
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