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Integrative analysis of functional genomic annotations and sequencing data to identify rare causal variants via hierarchical modeling

Identifying the small number of rare causal variants contributing to disease has been a major focus of investigation in recent years, but represents a formidable statistical challenge due to the rare frequencies with which these variants are observed. In this commentary we draw attention to a formal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Genet
Egile Nagusiak: Capanu, Marinela, Ionita-Laza, Iuliana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424902/
https://ncbi.nlm.nih.gov/pubmed/26005447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00176
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