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False discovery rates for rare variants from sequenced data
The detection of rare deleterious variants is the pre-eminent current technical challenge in statistical genetics. Sorting the deleterious from neutral variants at a disease locus is challenging because of the sparseness of the evidence for each individual variant. Hierarchical modeling and Bayesian...
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| Veröffentlicht in: | Genet Epidemiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711769/ https://ncbi.nlm.nih.gov/pubmed/25556339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21880 |
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