טוען...
Identification of Rare Causal Variants in Sequence-Based Studies: Methods and Applications to VPS13B, a Gene Involved in Cohen Syndrome and Autism
Pinpointing the small number of causal variants among the abundant naturally occurring genetic variation is a difficult challenge, but a crucial one for understanding precise molecular mechanisms of disease and follow-up functional studies. We propose and investigate two complementary statistical ap...
שמור ב:
| הוצא לאור ב: | PLoS Genet |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263785/ https://ncbi.nlm.nih.gov/pubmed/25502226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004729 |
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