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UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)

The mechanism by which ultraviolet (UV) wavelengths of sunlight trigger or exacerbate the symptoms of the autoimmune disorder lupus erythematosus is not known but may involve a role for the innate immune system. Here we show that UV radiation potentiates STING (stimulator of interferon genes)-depend...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kemp, Michael G., Lindsey-Boltz, Laura A., Sancar, Aziz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424351/
https://ncbi.nlm.nih.gov/pubmed/25792739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649301
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