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Variable Region Identical IgA and IgE to Cryptococcus neoformans Capsular Polysaccharide Manifest Specificity Differences

In recent years several groups have shown that isotype switching from IgM to IgG to IgA can affect the affinity and specificity of antibodies sharing identical variable (V) regions. However, whether the same applies to IgE is unknown. In this study we compared the fine specificity of V region-identi...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Janda, Alena, Eryilmaz, Ertan, Nakouzi, Antonio, Pohl, Mary Ann, Bowen, Anthony, Casadevall, Arturo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424345/
https://ncbi.nlm.nih.gov/pubmed/25778397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.618975
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