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Variable Region Identical Immunoglobulins Differing in Isotype Express Different Paratopes
The finding that the antibody (Ab) constant (C) region can influence fine specificity suggests that isotype switching contributes to the generation of Ab diversity and idiotype restriction. Despite the centrality of this observation for diverse immunological effects such as vaccine responses, isotyp...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471687/ https://ncbi.nlm.nih.gov/pubmed/22930758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404483 |
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