Generation of biologically active anti-Cryptococcus neoformans IgG, IgE and IgA isotype switch variant antibodies by acridine orange mutagenesis

Administration of MoAbs to Cryptococcus neoformans capsular glucuronoxylomannan (GXM) can alter the course of infection in mouse models. However, the effectiveness of these antibodies appears to depend on isotype and specificity. Comparison of isotype protection efficacy requires families of MoAbs w...

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Autores principales: SPIRA, G, PAIZI, M, MAZAR, S, NUSSBAUM, G, MUKHERJEE, S, CASADEVALL, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1996
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200522/
https://ncbi.nlm.nih.gov/pubmed/8809131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1996.d01-786.x
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