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Cryptococcus neoformans Virulence Gene Discovery through Insertional Mutagenesis
Insertional mutagenesis was applied to Cryptococcus neoformans to identify genes associated with virulence attributes. Using biolistic transformation, we generated 4,300 nourseothricin (NAT)-resistant strains, of which 590 exhibited stable resistance. We focused on mutants with defects in establishe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387659/ https://ncbi.nlm.nih.gov/pubmed/15075272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.2.420-429.2004 |
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