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Cryptococcus neoformans Virulence Gene Discovery through Insertional Mutagenesis

Insertional mutagenesis was applied to Cryptococcus neoformans to identify genes associated with virulence attributes. Using biolistic transformation, we generated 4,300 nourseothricin (NAT)-resistant strains, of which 590 exhibited stable resistance. We focused on mutants with defects in establishe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Idnurm, Alexander, Reedy, Jennifer L., Nussbaum, Jesse C., Heitman, Joseph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC387659/
https://ncbi.nlm.nih.gov/pubmed/15075272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.3.2.420-429.2004
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