Kidney cancer is characterized by aberrant methylation of tissue specific enhancers that are prognostic for overall survival

PURPOSE: Even though recent studies have shown that genetic changes at enhancers can influence carcinogenesis, most methylomic studies have focused on changes at promoters. We used renal cell carcinoma (RCC), an incurable malignancy associated with mutations in epigenetic regulators, as a model to s...

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Bibliografski detalji
Izdano u:Clin Cancer Res
Glavni autori: Hu, Caroline Y., Mohtat, Davoud, Yu, Yiting, Ko, Yi-An, Shenoy, Niraj, Bhattacharya, Sanchari, Izquierdo, Maria C., Park, Ae Seo Deok, Giricz, Orsolya, Vellamkutla, Nishanth, Gundabolu, Krishna, Ware, Kristin, Bhagat, Tushar, Suzuki, Masako, Pullman, James, Liu, Shirley, Greally, John, Susztak, Katalin, Verma, Amit
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424050/
https://ncbi.nlm.nih.gov/pubmed/24916699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0494
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