An initiation codon mutation (AUG----GUG) of the human alpha 1-globin gene. Structural characterization and evidence for a mild thalassemic phenotype.

alpha-globin is encoded by two adjacent genes, alpha 1 and alpha 2. Recent evidence suggests that these genes are not equally expressed and that the alpha 2-globin gene encodes the majority of alpha-globin. This finding would predict that a thalassemic mutation of the alpha 2-globin gene would resul...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Moi, P, Cash, F E, Liebhaber, S A, Cao, A, Pirastu, M
Format: Artigo
Langue:Inglês
Publié: 1987
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC442398/
https://ncbi.nlm.nih.gov/pubmed/3680504
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires