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Deletions in the alpha-globin gene complex in alpha-thalassemic mice.
Three induced, heritable mutations in the mouse cause alpha-thalassemias. The adult alpha-globin genes on each mutant chromosome are no longer expressed. Embryos heterozygous for one normal and any of the three mutant chromosomes also seem to be deficient in embryonic alpha-globin-like x-globin, sug...
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Main Authors: | , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
1981
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC349325/ https://ncbi.nlm.nih.gov/pubmed/6950407 |
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