Deletions in the alpha-globin gene complex in alpha-thalassemic mice.
Three induced, heritable mutations in the mouse cause alpha-thalassemias. The adult alpha-globin genes on each mutant chromosome are no longer expressed. Embryos heterozygous for one normal and any of the three mutant chromosomes also seem to be deficient in embryonic alpha-globin-like x-globin, sug...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1981
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6950407/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7644 |
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