Deletions in the alpha-globin gene complex in alpha-thalassemic mice.

Three induced, heritable mutations in the mouse cause alpha-thalassemias. The adult alpha-globin genes on each mutant chromosome are no longer expressed. Embryos heterozygous for one normal and any of the three mutant chromosomes also seem to be deficient in embryonic alpha-globin-like x-globin, sug...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Whitney, J B, Martinell, J, Popp, R A, Russell, L B, Anderson, W F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1981
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349325/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6950407/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7644
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