DNA Damage Signaling Is Induced in the Absence of Epstein—Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA

Epstein Barr virus (EBV), like other oncogenic viruses, modulates the activity of cellular DNA damage responses (DDR) during its life cycle. Our aim was to characterize the role of early lytic proteins and viral lytic DNA replication in activation of DNA damage signaling during the EBV lytic cycle....

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Udgivet i:PLoS One
Main Authors: Wang'ondu, Ruth, Teal, Stuart, Park, Richard, Heston, Lee, Delecluse, Henri, Miller, George
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423948/
https://ncbi.nlm.nih.gov/pubmed/25950714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126088
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