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A Subset of Replication Proteins Enhances Origin Recognition and Lytic Replication by the Epstein-Barr Virus ZEBRA Protein

ZEBRA is a site-specific DNA binding protein that functions as a transcriptional activator and as an origin binding protein. Both activities require that ZEBRA recognizes DNA motifs that are scattered along the viral genome. The mechanism by which ZEBRA discriminates between the origin of lytic repl...

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Detalhes bibliográficos
Main Authors: El-Guindy, Ayman, Heston, Lee, Miller, George
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924361/
https://ncbi.nlm.nih.gov/pubmed/20808903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001054
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