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Accurate Computation of Survival Statistics in Genome-Wide Studies

A key challenge in genomics is to identify genetic variants that distinguish patients with different survival time following diagnosis or treatment. While the log-rank test is widely used for this purpose, nearly all implementations of the log-rank test rely on an asymptotic approximation that is no...

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Publicat a:PLoS Comput Biol
Autors principals: Vandin, Fabio, Papoutsaki, Alexandra, Raphael, Benjamin J., Upfal, Eli
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423942/
https://ncbi.nlm.nih.gov/pubmed/25950620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004071
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