Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation

High doses of bleomycin administered to patients with lymphomas and other tumors lead to significant lung toxicity in general, and to apoptosis of epithelial cells, in particular. Apoptosis of alveolar epithelium is an important step in the pathogenesis of bleomycin-induced pulmonary fibrosis. The F...

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Vydáno v:PLoS One
Hlavní autoři: Arish, Nissim, Cohen, Pazit Y., Golan-Gerstl, Regina, Fridlender, Zvi, Dayan, Mark Richter, Zisman, Philip, Breuer, Raphael, Wallach-Dayan, Shulamit B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423936/
https://ncbi.nlm.nih.gov/pubmed/25951185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126730
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