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Pharmacodynamics, Tissue Distribution, Toxicity Studies and Antitumor Efficacy of the Vascular Targeting Fusion Toxin VEGF(121)/rGel
As a part of an ongoing assessment of its mechanism of action, we evaluated the in vivo pharmacokinetics, tissue distribution, toxicity and antitumor efficacy of VEGF(121)/rGel, a novel fusion protein. Pharmacokinetic studies showed that VEGF(121)/rGel cleared from the circulation in a biphasic mann...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423739/ https://ncbi.nlm.nih.gov/pubmed/23022224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.09.017 |
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