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The Vascular-Targeting Fusion Toxin VEGF(121)/rGel Inhibits the Growth of Orthotopic Human Bladder Carcinoma Tumors

Vascular endothelial growth factor (VEGF) and its receptors (FLT-1 and KDR) are overexpressed by human bladder cancer cells and tumor endothelial cells, respectively. Strategies that target VEGF receptors hold promise as antiangiogenic therapeutic approaches to bladder cancer. A fusion protein of VE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mohamedali, Khalid A, Kedar, Daniel, Sweeney, Paul, Kamat, Ashish, Davis, Darren W, Eve, Beryl Y, Huang, Samuel, Thorpe, Philip E, Dinney, Colin P, Rosenblum, Michael G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550288/
https://ncbi.nlm.nih.gov/pubmed/16242074
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