Ubiquitinated Sirtuin 1 (SIRT1) Function Is Modulated during DNA Damage-induced Cell Death and Survival

Downstream signaling of physiological and pathological cell responses depends on post-translational modification such as ubiquitination. The mechanisms regulating downstream DNA damage response (DDR) signaling are not completely elucidated. Sirtuin 1 (SIRT1), the founding member of Class III histone...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Peng, Lirong, Yuan, Zhigang, Li, Yixuan, Ling, Hongbo, Izumi, Victoria, Fang, Bin, Fukasawa, Kenji, Koomen, John, Chen, Jiandong, Seto, Edward
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423681/
https://ncbi.nlm.nih.gov/pubmed/25670865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612796
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