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SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

DNA methylation and histone acetylation/deacetylation are distinct biochemical processes that control gene expression. While DNA methylation is a common epigenetic signal that inhibits gene transcription, histone deacetylation similarly represses transcription but can be both an epigenetic and nonep...

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Detalhes bibliográficos
Main Authors: Peng, Lirong, Yuan, Zhigang, Ling, Hongbo, Fukasawa, Kenji, Robertson, Keith, Olashaw, Nancy, Koomen, John, Chen, Jiandong, Lane, William S., Seto, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232929/
https://ncbi.nlm.nih.gov/pubmed/21947282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06147-11
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