A Role for the Tyrosine Kinase Pyk2 in Depolarization-induced Contraction of Vascular Smooth Muscle

Depolarization of the vascular smooth muscle cell membrane evokes a rapid (phasic) contractile response followed by a sustained (tonic) contraction. We showed previously that the sustained contraction involves genistein-sensitive tyrosine phosphorylation upstream of the RhoA/Rho-associated kinase (R...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mills, Ryan D., Mita, Mitsuo, Nakagawa, Jun-ichi, Shoji, Masaru, Sutherland, Cindy, Walsh, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423659/
https://ncbi.nlm.nih.gov/pubmed/25713079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633107
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