Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase.

Depolarization of the sarcolemma of smooth muscle cells activates voltage-gated Ca2+ channels, influx of Ca2+ and activation of cross-bridge cycling by phosphorylation of myosin catalysed by Ca2+/calmodulin-dependent myosin light-chain kinase (MLCK). Agonist stimulation of smooth muscle contraction...

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Main Authors: Mita, Mitsuo, Yanagihara, Hayato, Hishinuma, Shigeru, Saito, Masaki, Walsh, Michael P
Formato: Artigo
Idioma:Inglês
Publicado: 2002
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222588/
https://ncbi.nlm.nih.gov/pubmed/12023886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020191
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