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Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice.
Mice with a homozygous deletion in their Tap-1 gene (-/- mice) express very low levels of cell membrane major histocompatibility complex class I molecules and have < 1% peripheral CD8+ T cells. We show that these -/- mice but not their +/- littermates display strong primary syngeneic anti-H-2Kb a...
Tallennettuna:
Päätekijät: | , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
1994
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC44235/ https://ncbi.nlm.nih.gov/pubmed/8022816 |
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