Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels

BACKGROUND: RNA-sequencing (RNA-seq) is a powerful technique for the identification of genetic variants that affect gene-expression levels, either through expression quantitative trait locus (eQTL) mapping or through allele-specific expression (ASE) analysis. Given increasing numbers of RNA-seq samp...

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Détails bibliographiques
Publié dans:Genome Med
Auteurs principaux: Deelen, Patrick, Zhernakova, Daria V, de Haan, Mark, van der Sijde, Marijke, Bonder, Marc Jan, Karjalainen, Juha, van der Velde, K Joeri, Abbott, Kristin M, Fu, Jingyuan, Wijmenga, Cisca, Sinke, Richard J, Swertz, Morris A, Franke, Lude
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423486/
https://ncbi.nlm.nih.gov/pubmed/25954321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0152-4
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