Recombinant interferon gamma augments phagocyte superoxide production and X-chronic granulomatous disease gene expression in X-linked variant chronic granulomatous disease.

We examined the potential of interferon gamma (IFN-gamma) to ameliorate the physiologic defect of chronic granulomatous disease (CGD) by studying its effects on CGD phagocyte superoxide generation, NADPH oxidase kinetics, cytochrome b559 content, and expression of X-CGD (the gene for the X-linked di...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Ezekowitz, R A, Orkin, S H, Newburger, P E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2821069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113153
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