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Regulation of immunoglobulin production in hyperimmunoglobulin E recurrent-infection syndrome by interferon gamma.

The hyperimmunoglobulin E recurrent-infection (Job) syndrome (HIE) is a congenital disorder characterized by high serum IgE, chronic eczematoid dermatitis, and recurrent infections. We examined the effect of interferon gamma (IFN-gamma) on excessive IgE production in HIE patients. Spontaneous in vit...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: King, C L, Gallin, J I, Malech, H L, Abramson, S L, Nutman, T B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298649/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2513574/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.24.10085
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