Organ specific cytokine therapy. Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-gamma to the human lung.

In the context of the central role of the alveolar macrophage in host defense of the respiratory epithelial surface, and the ability of IFN-gamma to activate mononuclear phagocytes, we have evaluated strategies to use rIFN-gamma to activate human alveolar macrophages in vivo. To accomplish this, rIF...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Jaffe, H A, Buhl, R, Mastrangeli, A, Holroyd, K J, Saltini, C, Czerski, D, Jaffe, H S, Kramer, S, Sherwin, S, Crystal, R G
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1991
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296032/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115291
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