Organ specific cytokine therapy. Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-gamma to the human lung.

In the context of the central role of the alveolar macrophage in host defense of the respiratory epithelial surface, and the ability of IFN-gamma to activate mononuclear phagocytes, we have evaluated strategies to use rIFN-gamma to activate human alveolar macrophages in vivo. To accomplish this, rIF...

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Bibliografische gegevens

Gepubliceerd in:	J Clin Invest
Hoofdauteurs:	Jaffe, H A, Buhl, R, Mastrangeli, A, Holroyd, K J, Saltini, C, Czerski, D, Jaffe, H S, Kramer, S, Sherwin, S, Crystal, R G
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical Investigation 1991
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1905329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115291
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