Defective antigen presentation and novel structural properties of DR1 from an HLA haplotype associated with 21-hydroxylase deficiency.

We have segregated DR1+ individuals into two categories according to whether or not their class II+ cells stimulated T lymphocyte clones specific for or restricted to DR1. In a majority of cases (87%), failure to stimulate was a property of cells having the B14;DR1 haplotype and/or nonclassical 21-h...

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Pubblicato in:	J Clin Invest
Autori principali:	Davis, J E, Rich, R R, Van, M, Le, H V, Pollack, M S, Cook, R G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC442338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2443540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113194
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